Chorionic gonadotropin (CG) is a hormone that is produced by chorionic tissue immediately after implantation. Normally, it is present in the body only during pregnancy. Thanks to medical advances, this hormone is created artificially for the purpose of treating anovulation (a cycle disorder that makes natural conception difficult). Why and when are hCG injections indicated? What is the result of such therapy?

Mechanism of action of hCG injection

Chorionic gonadotropin is involved in the synthesis of sex hormones, has a positive effect on the process of egg maturation and the key event of the cycle - ovulation. It is used to stimulate the release of the oocyte, if for some reason this process does not occur independently and anovulatory cycles are observed (rapid tests for ovulation are negative).


An injection of hCG promotes ovulation and supports the functioning of the corpus luteum (a temporary endocrine gland that produces the hormone progesterone until the 16th week). Previously, in the first phase of the cycle, follicle growth is stimulated under the influence of an estrogen substitute. When ultrasound shows its maturation to 2.5 cm in diameter, an injection of human chorionic gonadotropin is given. It is taken into account that two days have passed since the last dose of the stimulant Clostilbegit.

Ovulation occurs 1-1.5 days after the administration of the hormonal substance. Within two days, a period favorable for fertilization begins, which future parents should take advantage of. A woman’s own feelings, as well as a special pharmacy test, will tell her about the moment of ovulation. It will show a reliable result before the hCG injection, after which the rupture of the follicle can be seen by ultrasound.

How long the drug is eliminated from the body depends on individual characteristics. Typically, no traces of the substance are detected within 3-5 days. To do this, you should drink more fluid.

Types of hCG

HCG injection may be needed for:

  • stimulation of follicle rupture after treatment with Clostilbegit;
  • maintaining the life of the corpus luteum;
  • support pregnancy until the 16th week, until the placenta is formed.

To produce hCG preparations, proteins extracted from the urine of expectant mothers are used. In Russia you can purchase domestic and imported products. They are prescribed by doctors strictly according to indications. Self-medication can lead to hormonal disorders in the female body.



The dosage of hCG drugs is selected individually and is 500, 1000, 1500, 5000, 10000 units. The following drugs are distinguished by name: Pregnil, Horagon, Ecostimulin, human chorionic gonadotropin. The cost of drugs depends on the manufacturer, pharmacy markups, and dosage. On average, an HCG injection will cost 1,500 rubles.

In what cases is it prescribed?

Indications for injections of hCG medications:

  • anovulatory cycles;
  • supporting the functioning of the corpus luteum;
  • preparation for IVF at the stage of ovulation stimulation;
  • threat of pregnancy failure in the early stages;
  • history of recurrent miscarriage;
  • menstrual irregularities.

Stimulation with hCG drugs is indicated for underdevelopment of the genital organs, dysfunction of the hypothalamus and pituitary gland. In gynecology, they can additionally be prescribed for dysmenorrhea and menstrual pain associated with this pathology, nausea, and loss of consciousness.

Contraindications to hCG injection

When prescribing the drug, the doctor takes into account the patient’s age, health status and existing contraindications:

  • individual intolerance to the components of the product;
  • a number of diseases of the endocrine system, including the thyroid gland;
  • early menopause;
  • oncopathology of the female reproductive system;
  • tendency to thrombosis;
  • lactation period;
  • adhesions in the pelvis.

If there are contraindications or as prescribed by a doctor, ovulation stimulation is performed without the administration of hCG, only through the administration of Clostilbegit. In this case, the follicle bursts on its own after maturation, which is shown by an ovulation test. However, this does not always happen.


Instructions for use of injection

HCG preparations are produced in the form of a ready-made solution or components for its preparation (powder and water). The injection should be entrusted to a physician, since the place of intramuscular injection is the abdominal area. The dosage and time of administration are selected by the obstetrician-gynecologist. Most often, drugs are used in dosages of 1000, 5000, 10000 units.

Preparation for the procedure

After the injection of the hormone, the likelihood of pregnancy is very high, so it is worth preparing for the procedure in advance. To do this, it is important to get rid of bad habits and stress, and establish a healthy lifestyle. Normalization of weight plays an important role - its excess and deficiency can become an obstacle to successful conception and pregnancy. In parallel, it is recommended:

  • testing the hCG drug for individual intolerance;
  • testing for immunological compatibility with a partner, STIs;
  • examination by a therapist;
  • Ultrasound of the uterus and appendages;
  • diagnostics of pipe patency;
  • a course of hormonal therapy and hysteroscopy (if necessary);
  • checking the quality of the future father's sperm (spermogram).


After collecting anamnesis, the doctor determines the type of drug, prescribes its dosage and time of administration. On the specified day, the patient comes to the medical office for an injection.

How is the required dose selected?

The dosage is determined depending on the goal set by the doctor. An injection of hCG to stimulate ovulation is given with a dosage of 5000 units after detection of a dominant follicle. Superovulation before IVF is induced using the drug at a dosage of 10,000. The ovulation process is monitored by ultrasound. For maintenance therapy, dosages of 500 and 2000 IU are used. Injections are indicated on days 3, 6, 9 after ovulation.

If there is a threat of miscarriage in the early stages, make sure that there is no ectopic pregnancy (see also: hCG level in the early stages of ectopic pregnancy). Initially, the drug is administered at a dosage of 10,000 IU, and then 5,000 weekly. Therapy can last up to 14 weeks. In parallel, to maintain the desired level of progesterone, Duphaston or Utrozhestan are indicated (we recommend reading: how to take Duphaston: before or after meals?).

How and when is the injection given?


The drug is administered intramuscularly with an insulin syringe with a thin needle. The doctor determines where to inject. To stimulate ovulation, it is placed in the stomach, for which a distance of 2 fingers is removed from the navel to the side. The area is treated with alcohol. Then the skin fold is pinched and the syringe needle is inserted. An alternative for injections is the buttock area.

When stimulating ovulation, gonadotropin will perform its functions if the injection is given 1-1.5 days before expected ovulation. This process is monitored by ultrasound, the injection is given 10-14 days after the start of the menstrual cycle. The rupture of the follicle occurs precisely during the period when the injection is given. The injection does not affect subsequent cycles.

To maintain the function of the corpus luteum, pregnant women may be prescribed maintenance therapy with hCG. Typically, injections are given 3, 6, 9 days after the follicle ruptures.

When diagnosing pregnancy, the hCG level is constantly monitored. If its level decreases or there is a threat of miscarriage, maintenance therapy is indicated. The dosage is selected depending on the symptoms, tests, and the woman’s health condition.

What side effects might there be?

Side effects after an injection of hCG, which are observed in case of disruption of the administration process and overdose:

  • untimely ovulation, which, if the endometrium is unprepared, leads to termination of pregnancy;
  • accumulation of fluid in the abdominal cavity;
  • allergy manifestations from the skin, respiratory organs;
  • depression;
  • irritability;
  • fast fatiguability.

The most serious complication is ovarian hyperstimulation syndrome, in which many follicles grow at the same time. They do not burst, but develop into cysts, which is dangerous to health and leads to cardiac and respiratory failure and other serious consequences. Concomitant use of the drug with glucocorticosteroids in large dosages is not recommended.

If pregnancy does not occur as a result of therapy, you need to prepare for further treatment. Perhaps the long-awaited conception will happen naturally 2-3 months after hormonal intervention. Modern reproductive specialists have enough technology at their disposal to help a woman become a mother.

Human chorionic gonadotropin is a hormone necessary for the fertilization of an egg and maintenance. Sometimes a woman's body produces too little hCG, which prevents her from becoming pregnant. Then synthetic analogues of the hormone are used in the form of an injection.

HCG preparations are made from proteins in the urine of pregnant women. The hormone stimulates the synthesis of progesterone and estrogen - the main hormones that help form the corpus luteum and attach the embryo to the wall of the uterus, and then preserve the fetus until the placenta forms.

The drugs are available in the form of an injection solution and have the following names: Pregnil, Menogon, Novarel. The injection is given in the abdominal area with a syringe with a short insulin needle.

HCG injections stimulate the ovulatory process and are used for the following pathologies:

  • Impaired ovarian function resulting from a malfunction of the hypothalamus and pituitary gland.
  • Dysmenorrhea (menstruation accompanied by severe dizziness and weakness).
  • Infertility, which is anovulatory in nature. That is, there is no dominant one.
  • Insufficient level of functioning of the corpus luteum.
  • Miscarriage (constant miscarriages or frozen pregnancies).
  • Preparation for in vitro fertilization.
  • Maintaining pregnancy.

There are contraindications for the use of such stimulation:

  • Various tumors, cysts in the ovaries.
  • Early menopause.
  • Lactation.
  • Obstruction of the fallopian tubes.
  • Diseases of the adrenal glands.
  • Tendency to thrombosis.
  • Individual intolerance.

Important! For patients with heart and kidney failure, hormones are prescribed only after a thorough examination!

HCG injection 10000 for stimulation

If a woman has impaired egg maturation functions, ovulation does not occur. The reasons for this are: polycystic disease, tumors, prolonged stress. The following situations are usually observed:

  • The follicles do not mature at all.
  • The follicles do not mature completely.
  • The follicle matures, but the egg does not leave the corpus luteum.

The hCG injection is designed to help the formation of the follicle and stimulate the release of the egg.

Before using the hormone, a woman undergoes examination:

  • Tests for hormone levels.
  • Pipe patency examinations.

The hormone is administered when the doctor has determined the development of a dominant follicle on an ultrasound scan at a dosage of 1500-5000 units to stimulate its growth. To stimulate super ovulation in preparation for IVF, hCG is administered once in a dose of 10,000 units.

Ovulation should occur 24-36 hours after the injection. The process is monitored using ultrasound. If ovulation does not occur, then the amount is increased in the next cycle. The exact dosage is determined by the doctor for each specific case.

Important! Self-prescription of hormone therapy is prohibited, as this can lead to serious health consequences.

During ovulation

After the follicle bursts and the egg is released, to further maintain its vital activity and ability to fertilize, the doctor prescribes hCG injections.

Injections are given on days 3, 6 and 9 after ovulation at a dosage of 5000 units. This is necessary to maintain the corpus luteum and help implant the embryo.

During pregnancy

When pregnancy occurs, hCG is administered to prevent miscarriage or miscarriage.

Indications for this are:

  • Risk of miscarriage.
  • A sharp drop in hormone levels.

The hCG level is checked over time, since low levels may occur in the early stages, then they increase.

Important! Before the injection, it is necessary to perform an ultrasound to exclude ectopic pregnancy.

If the pregnancy is intrauterine, then to preserve it, 10,000 units of the drug are first administered, then 5,000 units twice a week. Treatment can last from 8 to 14 weeks, depending on the patient’s condition and hormonal levels. At the same time, Duphaston is prescribed to maintain progesterone levels.

How long will it take to ovulate?

Usually occurs 24-36 hours after administration of the hormone. During this time, for pregnancy to occur, sexual intercourse must occur every day.

Ovulation does not always occur after the injection; sometimes the corpus luteum continues to grow and turns into a cyst. Also, stimulation does not guarantee the onset of your own ovulation in the following months.

Thus, the hCG injection is a one-time stimulation procedure, and not a treatment for infertility.

When to take the test

The level of the hormone increases already on the first day after the injection, so it makes no sense to carry out ovulation tests within three days, as they will be false positive.

You need to check the onset of ovulation 3 days after the procedure.

When to test your hCG level

When pregnancy occurs, hCG levels begin to rise. A strong decrease (20%) indicates serious problems:

  • Risk of miscarriage.
  • Ectopic pregnancy.
  • Delayed fetal development.
  • Placental insufficiency.

To identify these pathologies, an ultrasound scan is necessary before starting hormonal treatment.

Normally, the hormone level constantly increases until the 11th week, then gradually decreases and remains unchanged throughout the entire period of gestation. For an accurate diagnosis, it is necessary to take repeated tests in the same laboratory.

HCG norms in honey/ml:

  • Non-pregnant - 0-5.
  • 1-2 weeks - 25-155.
  • 3-4 weeks - 150-4800.
  • 4-5 weeks - 2500-82000.
  • 5-6 weeks - 23000-150000.
  • 6-7 weeks - 30000-230000.
  • Week 7-10 - 21000-290000.
  • 11-14 weeks - 6000-100000.
  • 16-21 weeks - 4000-80000.
  • 21-39 weeks - 2700-76000.

The first increase is recorded after 11 days of conception, the level doubles every 48 hours. At the level of 1000 units, the fertilized egg is visualized during ultrasound. To confirm the normal course of pregnancy, tests are performed every two days. Indicators may be above normal if:

  • Multiple pregnancy.
  • Gestose.
  • Diabetes mellitus.
  • Down syndrome.

This may also indicate an incorrect determination of the gestational age.

Before donating blood for the hormone, you must meet certain conditions:

  • Take the test at the same time.
  • Do not drink alcohol or smoke.
  • Stop taking medications.
  • Avoid physical activity.
  • For several hours you should not take food or liquids other than water.

Possible complications

A hormone injection is an intervention in the natural processes of the body. Therefore, the following side effects often occur:

  • Ovarian cyst.
  • Vein thrombosis.
  • Ascites (accumulation of fluid in the abdominal cavity).
  • Hyperstimulation syndrome, which causes breathing problems, palpitations, abdominal pain, and dropsy.

Individual reactions may also occur in the form of nausea, vomiting, indigestion, pain in the lower abdomen and lower back, mood swings, and depression. These symptoms disappear after treatment ends.

Important! Hyperstimulation syndrome requires urgent medical attention and is treated in a hospital.

An HCG injection is a necessary support for ovulation and subsequent pregnancy. It is prescribed if a woman does not produce the hormone in sufficient quantities for some reason.

The dosage and regimen of use are chosen by the doctor, depending on the goals and health status of the woman. Typically, pregnancy after such stimulation occurs in the first two months. It should be remembered that the hCG injection is not a means of treating infertility, but a one-time stimulation.

You might find the following video useful:

Now that many couples have problems conceiving, the ability to induce pregnancy is of great importance. One such method is induction ovulation after hCG.

Is a repeating sequence of physiological processes. First, the inner lining of the uterus that is not useful for feeding the embryo is removed. Then one of the primary follicles begins its journey to maturity. The inner layer of the uterus is restored, ready to receive a fertilized egg.

After reaching certain growth parameters, the egg leaves the ovary and travels along the fallopian tube. From the devastated follicle, a follicle is formed that supports the resulting pregnancy with hormones. If conception does not occur, the circle closes and menstrual bleeding begins. This cycle of changes is called ovulatory. But this doesn't always happen. Normally, a healthy woman can go through 1-2 menstrual cycles without releasing an egg. Such periods are called anovulatory periods. Why is this happening? Mechanisms of anovulation development:

  • There is a physical obstacle to the release of the egg (in polycystic ovarian sclerosis syndrome).
  • The follicle does not have time to mature completely (if the cycle is too short).
  • The egg does not develop and does not reach viability (due to dysfunction of hormonal regulation)

Several methods are used to achieve ovulation:

  • Normalization of the work and rest regime of the diet.
  • Surgical treatment.
  • one or more drugs.

After a detailed examination of the couple (the latest spermogram result must be within normal limits), the doctor may decide to carry out drug stimulation of ovulation (induction). There is a wide range of medicines for this. One of them is hCG. Like other induction methods, it can only be prescribed by a doctor. This also applies to the choice of dosage of the administered agent.

The expected ovulation after hCG is realized in full because its effect is similar to the effect of luteinizing hormone. Under its influence, the egg matures and breaks through from the ovary. Particularly important is the effect on the body aimed at creating conditions for a favorable course of pregnancy when it occurs. It not only potentiates ovulation, but also prevents cystic degeneration of follicles capable of normal development and regression of the corpus luteum. Therefore, it can also be used after fertilization.

How long does it take to ovulate after a hCG injection?

To select the day of administration of this drug, it is necessary to be guided by the results of instrumental (ultrasound) and laboratory (hormonal status) methods, and not just calendar ones. Correctly chosen timing of induction will lead to a positive result. It is determined by achieving the optimal follicle size. Ovulation after the administration of hCG will appear after 24-48 hours.

Taking into account the speed of development of the effect from the administration of the drug, the life expectancy of the sperm and egg, sexual life for couples planning to conceive naturally is recommended according to an individual schedule prescribed by a doctor, taking into account physiological characteristics. This is where a good spermogram comes in handy.

Ovulation test after hCG injection

It is not the fact of its occurrence that shows, as it may seem. It reflects fluctuations in the level of Luteinizing Hormone (LH). It is its increase that can be interpreted as the release of the egg from the follicle. But this opinion is wrong.

Such an increase can be observed in other cases of natural (dishormonal shift), artificial (administration of drugs) and food (taking phytohormones) genesis.

Due to the fact that the molecular structure of hCG is close to LH, the ovulation test after its administration will be positive, but it will not reflect the onset of ovulation after hCG, but the presence of the drug in the body. A similar reaction will be observed for about 10 days. Therefore, the first pregnancy test should be performed no earlier than 14-15 days after the date of expected conception.

In any case of taking hCG, you must remember:

  • Only a doctor can prescribe the drug (taking into account the characteristics of a woman’s particular body).
  • Not all forms of anovulation require this drug.
  • The timing of the administration of hCG, sexual intercourse, and ultrasound monitoring must be strictly observed.
  • This stimulation method is not a panacea and its effectiveness is not 100%.
  • To conceive, you need not only an egg, but also high-quality sperm.
  • Monitoring the onset of ovulation when taking hCG should be instrumental (ultrasound), and not laboratory (test).

Many patients are concerned about the answer to the question: “The hCG 5000 injection was performed, how long after ovulation?” To understand the principle of action of human chorionic gonadotropin, you need to carefully understand its properties.

This hormone is indispensable if a woman plans to conceive and carry a child. However, there are situations when not enough of it is produced naturally, and it is because of this that pregnancy is impossible. In such a situation, a doctor may prescribe an injection of a synthetic analogue of this hormone.

Ask your gynecologist when ovulation occurs after an hCG injection. Here, a lot depends on the amount of active substance and the individual characteristics of the expectant mother’s body.

HCG injections for ovulation are made from a protein structure contained in the urine of a woman carrying a baby. The substance can activate the natural production of sex hormones. HCG for injection can have different medical names - Menogon, Novarel, etc. The doctor performs an injection with a special insulin syringe into the groin area. The main indications for such a procedure can be considered:

  • Pathologies accompanied by ovarian dysfunction.
  • Painful periods, clear signs of PMS.
  • Infertility is associated with the lack of release of an egg or the formation of a dominant follicle.
  • Suppression of the corpus luteum.
  • Frequent cases of spontaneous abortion.
  • Stimulation of the formation of an active egg during preparation for the IVF protocol.

Ovulation

With some ovarian pathologies, ovulation is impossible and the patient is unable to become pregnant. This situation is possible due to polycystic disease, neoplasms, and even prolonged stress.

The follicle with the egg may not form at all or may not form completely. In some patients, a mature egg is not able to exit the corpus luteum. It is recommended that the patient be given an injection of hCG to activate the production of follicles and the formation of a healthy egg.

Immediately before the procedure, you must undergo a diagnostic test. If during an ultrasound examination the physician discovers that follicles are beginning to form, a hormone injection is prescribed at a dosage of 1500 - 5000 units. If the patient is preparing for artificial conception and superovulation is needed, a substance with a volume of 10,000 units is administered.

How long does it take for ovulation to occur after an HCG 10,000 injection? Doctors say that the egg is fully formed and leaves the ovary within 1-1.5 days after the procedure. To monitor the patient's condition, an ovulation test and ultrasound are performed. If the egg is not mature, it is recommended to increase the dosage in the next menstrual cycle.

A maximum of 36 hours after the injection of hCG 10,000, full ovulation should occur. If you are planning a pregnancy, try to have as many sexual acts as possible in a given period of time.

There are cases when, after the administration of the hormone, ovulation does not begin, but the corpus luteum continues to develop and gradually transforms into a cyst. An hCG injection is a single stimulation procedure, but not a method of treating infertility.

There is no need to take an ovulation test within 3 days after the injection, as it is guaranteed to be positive. If conception has occurred, the hCG hormone in the body begins to rise. A decrease in the concentration of the substance in the blood may indicate a threat of miscarriage, ectopic pregnancy, placental insufficiency, or pathologies of embryo development.

To determine the exact cause of the decrease in the production of the hCG hormone, the patient needs to undergo an ultrasound examination. With normal fetal development, the concentration of the hCG hormone increases until the 11th week, and then decreases and stops at a certain level until the baby is born.

Complications

Any introduction of a hormonal drug disrupts the natural processes in the body. As a result of an incorrectly selected concentration, the patient may experience complications - a cyst, fluid accumulation, thrombosis, hyperstimulation, accompanied by shortness of breath, abdominal pain, and strong heartbeat.

Some patients may experience nausea, vomiting, or depression after administration of hCG. As soon as the treatment is over, the unpleasant symptoms will disappear.

An injection of the hCG hormone is necessary to stimulate ovulation and further support pregnancy. This treatment is prescribed to patients who do not have enough natural hormones or have certain pathologies in the functioning of the ovaries.

The physician individually selects the appropriate course of therapy and dosage of the drug for each patient. Pregnancy should occur in the first few cycles after the injection.

Almost every woman who plans to get pregnant knows what hCG is. This one is after the egg is fertilized. However, this does not happen with anovulation. That is, problems arise with the further occurrence, maintenance and development of pregnancy.

An injection of hCG to stimulate ovulation is used after the doctor detects a dominant follicle. The injection allows it to grow to the required size and burst.

What is a hormone?

Human chorionic gonadotropin (hCG) is a specific human hormone that contains subunits such as alpha and. The second has no analogues in the body, so pregnancy tests are made on its basis. It is produced in the first weeks of embryo development. Its number is growing significantly. However, from the 11th week, the concentration of the hormone may decrease.

During this period, it is necessary to monitor the peculiarities of the course of pregnancy. Jumps in hCG levels may indicate pathologies of fetal development and the threat of miscarriage. If the amount of the hormone is insufficient, then the woman has an abortion or its onset becomes impossible.

HCG promotes the production of progesterone and estrogen. The formation of the corpus luteum, the proper development and attachment of the embryo to the uterine mucosa depend on these hormones. It is he who ensures the preservation of pregnancy even before the formation of the placenta.

Indications and contraindications for use of the product

HCG drugs have a luteinizing gonadotropic effect. They stimulate the onset of ovulation in women. They should be used if the patient has:

  • dysfunction of the gonads, provoked by improper functioning of the pituitary gland and hypothalamus;
  • anovulatory infertility (that is, lack of formation of a dominant follicle and development of the egg);
  • insufficient functionality of the corpus luteum;
  • recurrent miscarriage;
  • dysmenorrhea.

HCG injections are required for the normal formation of the placenta in a pregnant woman. Without drugs based on gonadotropins, it is impossible to stimulate ovulation and IVF.

But it is not always possible to use hCG-based medicine. Contraindications include:

  • hypersensitivity to the components of the product;
  • early menopause;
  • congenital or postoperative absence of the gonads;
  • neoplasm in the pituitary gland;
  • hormonally active tumors.

You should also not give hCG injections if you have thrombophlebitis, hypothyroidism, adrenal insufficiency, fallopian tube obstruction, ovarian cancer, or during breastfeeding. The medicine should be used very carefully in case of renal failure, bronchial asthma, migraine, pressure surges, cardiac ischemia, and also in adolescence.

Rules of application

Before you begin the procedure for administering hCG, you need to make sure that it is approved. It is important to follow these rules:

  • Check the degree of patency of the fallopian tubes. If there is a problem, then there is no point in carrying out the procedure. Patency can be determined using laparoscopy or other diagnostic methods.
  • Determine hormonal balance. Tests are taken on the 3rd day of the menstrual cycle. Based on the results, the dosage of stimulant medications can be adjusted.
  • Perform an ultrasound. This procedure will have to be carried out many times. It is imperative to determine a woman’s ovarian reserve.
  • Take a spermogram for your partner, as well as test the compatibility of the couple to conceive a child.

HCG injection 5000 units. most often used if a woman does not ovulate for some reason. In most cases, this dose is enough to start the process. It must be done intramuscularly. A woman can give an injection on her own if she knows how to do it. If this is not possible, then it is better to entrust the procedure to a specialist.

If an injection of hCG is to help stimulate ovulation, then it should be done in the abdomen. This method is faster and more convenient. In addition, an injection in the buttock is characterized by the fact that its pain is more pronounced.

The distance from the navel to the injection site is about 2 cm on the left and right sides. Next, you need to pinch the fold of skin and insert the needle into it all the way to the base. It should be short (preferably insulin). The hCG injection site must be disinfected.

In case of stimulation of ovulation, monitoring using ultrasound is indispensable. It is important to monitor the size of the dominant follicle. As soon as they are as acceptable as possible, an hCG injection is immediately given. It is he who starts the ovulation process. Regression of the follicles is prevented, so the development of cysts is prevented.

One injection is enough to stimulate ovulation. The effectiveness of the procedure is checked by ultrasound on the second or third day. It significantly increases the chance of getting pregnant.

Before stimulation, it is necessary to check the woman’s hormonal levels. Sometimes, to restore her menstrual cycle, it is enough for her to undergo a simple course of treatment without the use of hCG.

Features of the stimulation process

Any interference in the natural processes of the female body does not pass without a trace. All procedures with hormones must be carried out with the permission and under the supervision of doctors. Before prescribing an hCG injection, the specialist must find out the following data:

  • dynamics of follicle enlargement;
  • features of endometrial growth.

And he is also obliged to predict when ovulation should occur. In addition to the injection, the patient may be prescribed concomitant medications: Puregon or Clostilbegit. After the injection, ovulation occurs no later than 36 hours. The following drugs are suitable for injection: Pregnil, Chorionic Gonadotropin. The dosage of the drug is prescribed by the doctor. The most commonly used injection of hCG is 10,000 units.

During this period, it is necessary to have regular sexual intercourse with a partner in order to become pregnant. You should have sex every other day. Next, there is additional stimulation of the functionality of the corpus luteum, which initially ensures the success of pregnancy and embryo development.

How to choose the right dosage?

This question should be addressed to a doctor who has examined the patient and is familiar with the instructions for use. You should not use injections on your own. For the first time, 5000 units of hCG are usually prescribed. If this dosage does not give a positive effect, then it can be increased to 10,000 units, but in the next cycle.

If ovulation has occurred, which was confirmed by ultrasound, then the patient is indicated for additional stimulation of the functionality of the corpus luteum. is prescribed on days 3, 6 and 9 after the release of the egg. The dosage in this case is minimal - no more than 5000 units.

In the presence of recurrent miscarriage, the course of treatment using hCG is long - up to 14 weeks. The first dose of the drug is 10,000 units. Further, the rate decreases. A woman receives 2 injections per week, 5000 units each.

Possible side effects

After stimulation has been carried out, it is important to ensure that ovulation occurs. Sometimes the patient may experience ovarian hyperstimulation syndrome. The follicle simply cannot rupture and develops into a cyst. In addition, the administration of hCG can cause other side effects:

  • gastrointestinal disorders (diarrhea, constipation, nausea);
  • thromboembolism (blockage of blood vessels by a detached blood clot);
  • hydrothorax (accumulation of fluid in the pleural cavity, which is non-infectious);
  • gynecomastia (this symptom is typical for men and manifests itself in enlarged mammary glands);
  • increased sensitivity of the nipples.

The patient may also experience pain and a rash in the area of ​​hCG injection. There is also discomfort in the mammary glands and fever. However, after the stimulation stops, all unpleasant sensations disappear.

Overdose and special instructions for the use of hCG

An overdose of hCG can be accompanied by ovarian hyperstimulation syndrome, which negatively affects a woman’s overall health. That is, the patient develops an excessive number of follicles, which over time degenerate into cysts. Treatment of all side effects is symptomatic.

It is important to remember that long-term use of hCG-based drugs is fraught with the formation. The likelihood of multiple embryos increases (development of multiple pregnancy). During treatment, as well as for a week after its completion, pregnancy tests may show an erroneous result.

If there have already been several unsuccessful attempts at stimulation, in which the dosage of the drugs used was gradually increased, then it is necessary to stop the process and undergo additional tests. After this, treatment methods are reviewed.

If the drug Clostilbegit is used for stimulation, it is recommended to use it no more than 5-6 times throughout life. Otherwise, ovarian wasting syndrome will occur and the woman will not be able to use her own eggs even for artificial insemination.

If stimulation does not give the expected result and pregnancy does not occur, do not give up. Perhaps the long-awaited conception will occur naturally after 2-3 months. Moreover, now there are new reproductive technologies that allow a woman to become a mother.