These include joint pain, dental pain, and menstrual pain. The drug has anti-inflammatory and antipyretic properties. Available both in tablet form and in the form of suspensions.
Medicinal educational program
Sometimes our legislative bodies like to send drugs without re-registration, ban them from being imported into the country, and so on drag out bureaucratic bagpipes. What to do when your favorite pills disappear from pharmacy shelves?
- Do not panic.
- Ask your doctor if there is an analogue of your favorite medicine. If you can’t see a doctor, you can get all the information about the drug from the pharmacist at the pharmacy.
There is an analogue for any medicine. Substitutes are divided into:
- Generics – that is, the active substance is the same, but the names are different. The effect that such tablets have is no different from patented drugs. But the cost may be significantly lower.
- Complete analogue - that is, the effect of the medicine is similar, but the active ingredients are different. Costs can also vary significantly.
The drug "Nise". Generics
The main active ingredient of the drug "Nise" is nimesulide. What drugs with the same composition can the pharmacist suggest?
- Aponil is the active ingredient nimesulide. Available in the form of tablets with a dosage of 100 mg. Manufacturer: Cyprus company Melokemi LTD.
- Mesulide - produced in Romania by Rompharm. This is a soluble form for preparing a suspension. One sachet contains 2 g of the drug, the dosage is also 100 mg.
- Nimesil - manufacturer Italy. Soluble form, dosage 100 mg in 1 sachet.
- Nimesulide is produced by Romania and Macedonia. Soluble form.
- Nimika is a manufacturer in India. Presented in the form of tablets with a dosage of 50 mg and 100 mg.
- Nimulid - manufacturer India. Available in the form of lozenges, gel, or just tablets in various dosages.
All these drugs work the same way. Soluble forms “nimesil” and “nimesulide” begin to act faster. This is not a pharmacological feature of these drugs; soluble forms are simply absorbed faster into the mucous membranes of the mouth and stomach than tablet forms.
If the pain is severe or the body temperature rises sharply, then it is more advisable to use soluble forms of the drug.
The choice of drugs is sufficient, and if you don’t find Nise at the pharmacy, then you can safely buy any analogue from the list above.
Other drugs in the same class
There are medications in the same class as Nise - non-steroidal anti-inflammatory drugs. Prescribed for the same diseases as Nise.
- Denebol is presented on the market in 3 dosage forms - gel for external use, ampoules and tablets. The main active ingredient is roferocoxib. Indications for use: pain of various etiologies, rheumatoid and other arthritis, neurological diseases. Both injections and tablets are taken once a day. Manufacturer – India, Mepro Pharmaceuticals Pvt. Ltd.
- Movalis - active ingredient - meloxicam. In pharmacies it is presented in the form of tablets, rectal suppositories, injections. Dosage 7.5 and 15 mg. 1 ampoule or tablet per day is also prescribed. Produced in Germany by the Boehringer Ingelheim concern.
- Meloxicam - also available in tablets and injection solutions. Also prescribed is 1 tablet or injection per day. Do not use to treat children under 15 years of age.
- Arcoxia – indications – pain syndrome, treatment of arthritis of various etiologies and genesis. Available in 3 different dosages - 120 mg, 90 mg, 60 mg. Take 1 tablet per day.
These drugs are prescribed mainly for various problems with joints, muscles, ligaments, for the treatment of the spine, and neuralgia. The above medications have a strong analgesic and anti-inflammatory effect and can quickly reduce body temperature.
In this regard, they are superior to Nise. But if it is only necessary to reduce the temperature during an infectious disease, then it is better not to use these medications.
All drugs in this group have a lot of side effects and contraindications. Joint inflammation is a good reason to use Meloxicam, Denebol or Arcoxia. In this case, the potential benefit of the drug is much higher than the potential harm.
In the case of body temperature elevated to 38 degrees and a runny nose, their use is unjustified.
"Nise" and its analogues at elevated body temperature
Paracetamol or Ibuprofen will help relieve mild pain and reduce temperature during a cold. Both drugs belong to the same pharmacological class of substances – non-steroidal anti-inflammatory drugs.
They have weak analgesic properties, but are excellent at reducing body temperature. No worse than Nise or other nimesulide preparations. These drugs have few side effects and do not irritate the mucous membranes of the stomach and intestines.
Paracetamol and ibuprofen can be given to children almost from birth. These are over-the-counter drugs and should be in any mother's medicine cabinet.
Nise. conclusions
- If the pharmacy does not have the medicine you need, consult your pharmacist about replacing it with an analogue with the same active ingredient and in the same dosage.
- If you cannot find a complete analogue, then consult your doctor about replacing it with a drug that belongs to the same pharmacological group. Not with the pharmacist, but with the attending physician!
- Do not use strong drugs without a doctor's prescription. The body tends to get used to medications. And in the future the drug may simply not work.
Cheap analogues and substitutes for Nise Gel for children and adults
The drug Nise Gel has established itself as an effective medicine that eliminates pain. In addition to the gel, tablets and oral suspension can be found in pharmacies under this brand name. The drug is prescribed for children and adults as a non-steroidal anti-inflammatory drug.
The basis for the use of Nise gel is the treatment of symptoms of inflammatory diseases of the musculoskeletal system: articular syndrome, arthritis, osteoarthritis, osteochondrosis, radiculitis, lumbago, rheumatism, etc.
The medicine is manufactured in India. In Russia, its prices vary between 175–470 rubles. A review of medications with nimesulide showed that among medications both Russian and imported, you can find cheap analogues of nise gel.
Russian-made analogues
Let's consider close substitutes for Nise gel among drugs from domestic manufacturers. The table offers a comparison of prices and descriptions of similar medications.
Ukrainian substitutes
Cheap analogues of the drug Nise Gel produced in Ukraine have a different active ingredient, but similar indications for use. A list of modern medicines is presented below.
- Nobi gel. The product will solve the problem of how to replace the Nice gel. Effectively relieves pain, eliminates swelling and swelling. Indications for use: pain after injuries or bruises, tenosynovitis. The average price is 120–145 rubles.
- Fort gel. An inexpensive analogue of Nice gel with the active ingredient – ketoprofen. It is used topically to eliminate post-traumatic pain, sprains, and bruises. Sold as a gel in tubes of 30 and 50 g. The average price is 55–70 rubles.
Belarusian generics
Belarusian generics are an excellent option for replacing a cheap drug with nimesulide.
Other foreign analogues
Modern imported synonyms will help you choose an inexpensive analogue of Nise in tablets and other dosage forms.
- Aponil. The drug is produced in tablets. It is used to treat pain, reduce temperature, and for inflammatory processes of the musculoskeletal system. Country of origin: Cyprus. The average price is 110–130 rubles.
- Nimesil. The best imported analogue of Nise with a similar effect. The basis of the medicine is nimesulide. Release form: powder for preparing a drink, which is consumed orally. The drug is produced in Italy and Germany. The average price is 25–690 rubles.
- Nimulid. Non-steroidal anti-inflammatory drug with antipyretic and analgesic function. Available in the form of tablets, gel, suspension. Country of origin: India. The average price is 130–355 rubles.
- Nimika. Instant tablets. Indications for use: osteoarthritis, diseases of rheumatic origin, postoperative pain. Fever, dysmenorrhea. The drug is produced in India. The average price is 120–250 rubles.
This approach to choosing an anesthetic drug is unacceptable due to the presence of a wide range of contraindications. Children and patients with heart failure, kidney disease, diabetes mellitus and arterial hypertension need to be monitored by a doctor for a possible reaction to the drug.
Inexpensive analogues of Nise gel and tablets
Pain and inflammation cause a lot of unpleasant sensations, and when intense, they cause agony. In order to eliminate symptoms and treat inflammatory processes, drugs of the synthetic group are used, which include Nise, as well as its analogues.
About the drug
A drug that has an analgesic and anti-inflammatory effect in many pathological processes.
The effect of using a medicine is based on the body's reaction to its composition. The active substance is nimesulide.
Available in the form of regular and dispersible tablets, also in the form of medicinal powder for the preparation of suspension and gel for external use.
Regardless of the form of release, indications for use are pain and inflammation in diseases:
- arthritis of psoriatic or rheumatoid type;
- sciatica or radiculitis;
- joint disorders due to rheumatism or gout;
- spondyloarthritis or osteochondrosis;
- lumbago or arthritis;
- myalgia or arthralgia;
- feverish condition;
- inflammation of soft tissues after injuries;
- bursitis or tendon damage;
Nise tablets and suspension are used to relieve pain, dental pain, menstrual pain and headaches. Nise gel is recommended for traumatic injuries and after operations performed on muscles, bones or joints.
The instructions for use of the drug warn about the undesirable use of the drug in tablets and suspensions for pathologies:
- erosions or ulcers on the mucous membranes of the gastrointestinal tract;
- liver/kidney dysfunction;
- aspirin triad.
Gel Nise is not prescribed if the skin is affected by infection or dermatoses.
Absolute contraindications for any form of release of the analogue are considered to be the period of pregnancy/lactation and sensitivity to the existing composition.
The drug has many side effects, but they most often occur with an overdose or the presence of contraindications. In case of an adverse reaction, the patient experiences symptoms:
- disorders of the stomach and intestines;
- migraine;
- allergies (including anaphylactic shock);
- circulatory disorders.
The average price for Nise gel and tablets is 200 rubles, suspension powder is 300 rubles.
Similar medicines
If necessary (due to the high price, contraindications, side effects, etc.), you can replace Nise with analogues. Depending on the indications, as well as the reason for searching for a substitute, the doctor may prescribe analogs that are cheaper or more expensive than the original. It should be borne in mind that some analogues of this group are sold in pharmacy chains only with a prescription.
Nimesulide and Ibuprofen are substitutes that cost much less than the original.
Nimesulide
Direct analogue of Nise gel and tablets. The medicine is used for therapy for inflammatory diseases of the musculoskeletal system and other body systems. Also, tablets and gel for external application are used as a strong pain reliever for various forms of pain.
The active substance has a name identical to the name of the drug - Nimesulide. Tablets contain 100 mg. the main component and additional substances necessary to enhance the effect of the composition.
List of direct indications:
- osteoarthritis;
- dysmenorrhea;
- migraine;
- toothache;
- injuries to muscles, joints or bones;
- pathologies of the musculoskeletal system.
An analogue of Nise tablets is contraindicated in case of damage to the gastrointestinal mucosa, heart failure, and a substitute in the form of a gel is contraindicated in case of open wounds and infectious processes on the skin.
- children's age (up to 12 years);
- intolerance to the components of the composition;
- blood pathologies;
- kidney/liver diseases;
- alcohol addiction;
- allergy to one or more substances from the composition of the drug.
A cheap analogue of Nise can cause side symptoms:
- pain in the epigastric region, feeling of nausea, severe heartburn, change in stool;
- constant dizziness or drowsiness;
- erythema, rash or urticaria;
- slower removal of fluid from the body, swelling;
- thrombocytopenic purpura.
The price of the drug Nimesulide is from 80 rubles.
Ibuprofen
Another cheap analogue of Nise gel and other forms of release is Ibuprofen. The drug has a wide range of effects and is recommended for providing analgesic, antipyretic, and anti-inflammatory effects.
- tablets (extended, regular and for resorption);
- extended-release capsules;
- suspension;
- caviar gel
The active component of the analogue is ibuprofen.
Instructions for use include the following indications:
- signs of a viral disease (ARVI/flu);
- arthritis (psoriatic), osteoarthritis and spondylosis;
- migraine, myalgia and neuralgia;
- spinal artery syndrome, Barré-Lieu or nephrotic;
- bursitis, tendinitis and hematomas;
- hypotension, ankylosing spondylitis, fever;
- injury to soft tissue or bones.
An inexpensive analogue is also used for therapy for sprains of ligament tissue, arthritis (rheumatoid), articular syndrome or radiculitis.
The list of contraindications to the use of medications is extensive. The main contraindications for Ibuprofen include:
- the presence of ulcers or erosions on the walls of the stomach or intestines (except for the use of gel);
- sensitivity to the existing composition;
- pathologies of the optic nerve and deviations regarding the function of color visual perception;
- Asperin asthma;
- hypertension, amblyopia or scotoma;
- impairment of the full functioning of the kidneys/liver;
- heart failure;
- hemophilia, edema, leukopenia;
- third trimester pregnancy.
The Russian drug causes side effects that affect the nervous, digestive, circulatory and urinary systems. An allergic reaction is also possible.
The cost of medicines is from 70 rubles, depending on the form prescribed by the specialist.
Nimesil
An anti-inflammatory drug with an analgesic effect, Nimesil, is included in the list of drugs that are analogues of Nise.
The drug is produced only in the form of a powder for dissolution and preparation of a suspension. The active component is nimesulide.
- infectious inflammation;
- inflammatory and degenerative processes affecting the musculoskeletal system;
- gynecological, urological and vascular inflammatory pathologies;
- post-traumatic complications;
- dental diseases;
- migraine.
Nimesil has earned positive reviews for eliminating pain during menstruation and as an antipyretic.
- inflammatory processes in the gastrointestinal tract;
- installation of a shunt in the aorta;
- fever;
- intolerance to any constituent substances.
The body’s negative reaction to the Nise analogue is expressed in the following symptoms: heart rhythm disturbances, headaches, intestinal dysfunction and allergies.
The price for Nimesil is from 500 rubles.
Nimulid
A good analgesic and pain reliever is Nimulid, developed on the basis of nimesulide as an active ingredient. Among the drugs that replace Nise, Nimulid is considered one of the most effective; in addition, the drug has several release forms. Lingual, regular tablets and suspension. Also, the drug in the form of an ointment can replace Nise gel.
- arthritis of rheumatoid or psoriatic nature;
- bursitis, musculoskeletal injuries;
- osteochondrosis or spondyloarthritis;
- articular gouty syndrome;
- myalgia.
- erosive - ulcerative damage to the mucous membrane of the walls of the stomach or intestines;
- diseases developing in the liver or kidneys;
- tendency to allergies, including intolerance to the composition;
- pregnancy/lactation.
Side symptoms often include headaches and severe weakness. When treated with ointments, a local allergic reaction is possible.
The analogue is cheaper than Nise - from 170 rubles.
Aertal
The non-steroidal drug Airtal is a substitute for Nise in three main forms (tablets, gel and suspension). However, unlike Nise, Aertal contains the main component - aceclofenac, which eliminates pain and prevents the process of inflammation.
- periarthritis in the shoulder and shoulder blade area;
- lumbago;
- rheumatism progressing in soft tissues;
- osteoarthritis;
- dental pain;
- rheumatoid arthritis;
- ankylosing spondylitis.
The cream can be used to relieve swelling of tissues and eliminate pain of a limited nature (for example, due to injuries).
- damage to the walls of the gastrointestinal tract;
- hives;
- bronchospasm;
- medicinal rhinitis;
- liver dysfunction;
- circulatory pathologies;
- hyperkalemia;
- a woman carrying a fetus;
- breastfeeding;
- childhood.
Before starting treatment with Airtal, you should pay attention to signs of side effects associated with dysfunction of the stomach/intestines and nervous system. An allergic reaction is possible.
The price for Aertal is from 270 rubles.
Aceclofenac
The drug Aceclofenac with analgesic, antipyretic and anti-inflammatory effects belongs to the group of analogues of the drug Nise.
There is only one release form - tablets, which contain a medicinal substance - aceclofenac.
Indications for symptomatic therapy:
- spondylitis;
- arthritis;
- periarthritis;
- osteoarthritis;
- inflammation of soft tissues (rheumatoid).
- age of patients under 18 years;
- gastrointestinal pathologies associated with the presence of ulcers or erosions;
- aortic bypass;
- heart failure;
- lactation/pregnancy;
- allergy to the medicinal composition of the drug.
Side effects manifest themselves in the digestive tract, circulatory and nervous systems, as well as in the form of allergies.
The cost of the Nise analogue is from 230 rubles.
Conclusion
Taking into account all the features of treatment with drugs of this group, experts are of the opinion that Nise’s analogues have more disadvantages than the original. However, it is impossible to determine what is best for the patient in each specific case. Sometimes cheaper analogues are more effective than the original drug with a high cost. The effect of drugs on the body often does not depend on price, so the choice of drugs should be trusted only to the attending physician.
What substitutes for Nise medicine exist?
Often, instead of the original product, analogues of Nise are used. The widely advertised and effective analgesic, antipyretic and painkiller Nise, the analogues of which make up an impressive list, sometimes disappears from sale or seems quite expensive to the patient. The modern pharmaceutical industry produces not only patented and expensive original versions of drugs, but also their cheaper analogues, prudently provided with a different commercial name. Nise contains the active substance nimesulide, which is widely used in the manufacture of medications with a certain spectrum of action.
Having information about the active ingredient, you can easily find a substitute for Nise, which contains the same active substance (or another, but with a similar effect). The only thing that should not be forgotten is the inadmissibility of self-prescription of any medicine.
Before taking any medications, replacing a medicine prescribed by a doctor with a supposed analogue, you should definitely consult about the possibility of such a replacement.
Nimesulide and its areas of application
Any form of release of the original drug Nise includes the active substance nimesulide. Clinical studies have shown its high effectiveness not only as an anti-inflammatory and analgesic non-steroidal drug. This is an effective way to solve problems with joints, interarticular cartilage tissues, tendons, their bruises, injuries and inflammatory processes. The influence and side effects of the original medicine have been studied in a clinical setting. This made it possible to provide it with protective documents and a patent, but at the same time increased its cost.
Today, Nise is available in tablets, gel and suspension, and this has expanded the scope of its application. Nise tablets (50 or 100 mg), which have a pronounced analgesic effect, are available in blister packs of 10 pieces. Nise gel is a local preparation that is applied to the affected areas. The suspension is given to children aged 2 years and older. The active substance included in the medicinal product is used for:
- osteochondrosis;
- gout;
- joint inflammation;
- rheumatism of various etiologies;
- arthritis;
- sciatica;
- radiculitis;
- injuries, bruises and damage to articular segments.
The gel allows you to use the therapeutic effect of nimesulide in cases where it is necessary to minimize side effects, and the dislocation of the pathology is conducive to this.
The need to replace a medicine arises when the patient’s financial situation does not allow the purchase of expensive drugs, or an individual intolerance to any component included in the original drug is revealed. Finding an analogue of Nise is not difficult, the main thing is to select it professionally so that the replacement is complete. Analogues of Nise gel are no worse than the original.
Types of analogues
When choosing cheaper tablets, you should take into account certain subtleties that may not be in the distributed lists. They may not even be in the instructions for use that pharmacists follow. There are 2 types of similar medicines:
Their fundamental difference lies in the active substance used. Generic Nise is a medicine that uses nimesulide. In this case, the difference lies only in the availability of permits and cost. This is an inexpensive analogue of Nise in tablets. Cheap medicines are not patented, but are identical in terms of the nimesulide they contain.
Complete analogues include drugs that have a similar effect, but the active substance in them is different. Nise has certain contraindications, which the attending physician will certainly take into account. Another medicine may have additional or fundamentally different side effects, which only a specialist can take into account. The same applies to:
- influence on the ability to operate machinery and drive vehicles;
- interactions with other drugs;
- pharmacokinetics and characteristics of absorption and excretion from the body;
- possible allergic reactions to components added to a particular medicine.
In this regard, Russian analogues are preferable both in terms of cost and the content of additives in a particular preparation. In addition, the presence of professionally written instructions in Russian will help you understand the nuances of prescription and dosage.
The misconception that a cheap drug is less effective than an expensive one is wrong in the case of nimesulide-containing generics, but consulting a specialist on the specifics of dosage and administration will not hurt. The Russian-made analogue is no worse than the foreign original.
Positive and negative points
The undeniable advantages of replacing Nise with more affordable nimesulide-containing generics include the difference in cost, which sometimes significantly saves the patient’s money. The mode of action and technology of the drugs are practically no different from their expensive analogues. A person with a low income can afford treatment with the active substance prescribed to him.
Negative aspects include the lack of qualifications that are assigned to generics abroad, and sometimes the insufficient quality of purification of the components included in the medicine. This is due to the fact that patented drugs are produced by large pharmaceutical companies with new and technologically advanced equipment, and commercial analogues are produced by small enterprises whose production equipment may be outdated or simply of a lower class.
When purchasing a medicine with the same active substance, the likelihood of discrepancy is minimal. But when purchasing a drug that is not a steroidal anti-inflammatory, but is based on another active component, you can make a mistake in your choice and not get the desired result. Ointments are easier to choose because they are applied topically. You need to be careful with tablets, as they are taken orally and interact with vital organs (gastrointestinal tract, kidneys, urinary system).
Medicines containing nimesulide
Nimesulide is considered the main and most common generic Nise. It bears the name of the active substance it contains, is widely sold in retail and compares favorably in price. The list of drugs that can replace Nise is quite wide, and some substitutes cannot be found in any pharmacy. Therefore, the list of analogues is given in abbreviated form:
- Actasulide (NSAID of the sulfonanilide class);
- Ameolin (for the treatment of acute pain in primary dysmenorrhea and osteoarthritis);
- Aponil (with indications similar to Ameolin);
- Artron (Complex, Triactiv, Flex, Hondrex - on the recommendation of a doctor, depending on the nature of the pathology);
- Mesulide;
- Nimegesik, Nimesil, Nimesulide, Nimulid, Nimefast, Novolid (all names are derived from the name nimesulide, these drugs are full-fledged analogues of Nise);
- Structum (for osteoarthritis and osteochondrosis);
- Sulidin (wide-spectrum use for joint pathologies);
- Flolide;
- Hondra-sila (including warming ointment Hondra-sila and Hondra-sila ointment).
The price of these drugs is an order of magnitude lower, but replacing one drug with another, even similar ones, should be done with extreme caution. It is no coincidence that even some analogues have different indications for use. Nimesil is produced in Italy, Nimesulide - in Romania and Macedonia, Nimulid - in India. Some of them are water soluble and act faster, but the price of domestic drugs is less and therefore they are preferable.
What to remember when choosing an analogue
Any medicine can turn into poison and have a negative effect if the dosage is chosen incorrectly, the drug is chosen incorrectly, or low-quality counterfeit products manufactured in semi-handicraft conditions are purchased. In no case should the patient independently replace tablets or ointments.
This requires a specialist opinion. If you do not have the time or opportunity to see a doctor, you should at least consult with a pharmacist or carefully study the leaflet that is always included with the medication.
Neither very high nor extremely low cost is a fundamental indicator. You need to be guided only by the opinion of a specialist, who is based on considerations of the feasibility of use and his professional experience. Self-medication rarely leads to positive results and can often have a negative impact on the body's condition. Proper replacement of an expensive drug with a generic or full analogue is the key to successful treatment with lower material costs.
Nise tablets: what analogues of the drug are there?
Nise is an excellent pain reliever and antipyretic. This analgesic is prescribed during various diseases. It is popular for its ability to act quickly and delay the manifestations of pain for a long time.
It happens that this medical product is not available in pharmacies or it is more profitable for a person to buy its analogue (generic), then it is natural that he wants to know what can replace this product.
A little about Nise tablets
Nise has a wide spectrum of action and for this he is grateful to his active element, which is in its composition - nimesulide.
Each tablet contains it in 50 mg or 100 mg.
There are 10 pieces in a blister.
Nise is a medicinal non-steroidal drug that is available in the form of:
It is used to treat a variety of diseases of the joints, bones, and tendons. Nise tablets have a pronounced analgesic effect.
Since this medicinal product has an analgesic effect, it is often recommended for joint diseases:
In addition, doctors prescribe Nise for problems in the tendons and interarticular cartilaginous tissues.
- Bruises;
- Tendon restoration after injuries;
- During ligament rupture;
- Headaches;
- Toothaches;
- During periods of painful menstruation.
And this is a small list where Nise can be used.
Contraindications to the use of tablets:
- During the period of exacerbation of gastrointestinal diseases;
- Ulcers and bleeding of the digestive system;
- Malfunctions of the liver;
- "aspirin triad";
- Overt renal disease;
- During pregnancy;
- And during lactation;
- Nise tablets are prohibited for children under 12 years of age;
- Allergic reaction to one of the components of the product.
Inexpensive analogues of Nise
Everyone who buys this medicine at the pharmacy wants to know which analogues of Nise are in the “cheaper” category. There is a list of medicinal products that are similar in their action and properties to Nise tablets, and the price category is slightly lower.
The list of analogues of Nise tablets includes a lot of medications.
But, please note, this product is just an analogue of Nise.
Before replacing the original with a generic, consult your doctor.
List of similar drugs:
- Alit. This drug can relieve pain of various etiologies: headache, toothache, muscle and joint pain, periodic female pain. Prescribed for pharyngitis, tonsillitis, otitis. Inflammatory process in the musculoskeletal system. Pain after surgery. An infectious and inflammatory process accompanied by fever. Various colics: renal, hepatic, intestinal and the like. Contraindications: stomach and duodenal ulcers, problems with the liver and kidneys, glaucoma, obstructive diseases of the gastrointestinal tract, biliary and urinary tracts, paralytic ileus, myasthenia gravis, hypersensitivity to the components of the drug, pregnancy, lactation, children under 12 years.
- Amelin. It is used during acute pain, and is used by women for primary dysmenorrhea. Osteoarthritis with severe pain is treated.
- Aponil. Acute pain, primary dysmenorrhea, pain due to osteoarthritis. Contraindications: aspirin asthma, bleeding in the gastrointestinal tract, during periods of exacerbation of ulcers, severe disruptions in the liver and kidneys, 3rd trimester of pregnancy, children under 12 years of age, prohibited during breastfeeding, allergic reactions to Aponil.
- Naysik. Indicated for diseases: osteoarthritis, osteoarthritis, inflammation due to injuries (dislocation, bruise, stretch mark, etc.). Used by dentists, gynecologists, ENT specialists. Calms feverish conditions. Used during recovery after surgery. Contraindications: allergies to the drug, pregnancy and lactation, liver failure, severe forms of blood clotting and kidney disease, periods of exacerbation of diseases in the gastrointestinal tract.
- Negan. Its use is similar to Aponil and Amelin.
- Nimegesik.
- Nimesil. Treatment of acute pain, dysmenorrhea, is used as a means of second action. Contraindications: allergy to the product, alcoholism and drug addiction. Severe forms of blood clotting, heart failure, kidney and liver function. During periods of elevated body temperature. 3rd trimester and lactation. Children under 12 years old. Ulcer, an active form of the disease in the gastrointestinal tract.
- Nemisin.
- Nimesulide. One of the cheapest analogues of Nise tablets. This drug is recommended by dentists and gynecologists to their patients. It is able to relieve pain during headaches, rheumatoid arthritis, and osteochondrosis. Can be used in post-traumatic periods.
Contraindications: ulcers, exacerbations of disease in the gastrointestinal tract, renal and liver failure.
Severe conditions: heart failure, problems with blood clotting. Allergic reactions to components in Nimesulide.
Pregnancy 3rd trimester, breastfeeding period.
Also, should not be used for alcoholism, drug addiction, or fever.
- Nimid. Used to treat pain in bones, joints, and muscles. It has established itself as a good analgesic after surgery. Relieves toothache, pain during menstruation, used in ENT practice. Contraindicated in patients with a tendency to bleeding, suspected surgical pathology, gastrointestinal problems, ulcers, fever, etc.
- Nimujet. Treats pain of various origins. Contraindications: active peptic ulcer, moderate or severe liver and kidney failure, hypersensitivity to the drug.
- Nimulid.
- Nimika. Manufactured as dispersible tablets. One package contains 20 pieces. Produced in India. It has antipyretic and anti-inflammatory properties.
- Pansulide.
- Sisnaide. Treats rheumatic joint pain and non-joint pain in soft tissues. Pain caused by an inflammatory process in the body. Used after injuries and in the postoperative period. Practices in gynecological and dental fields. Removes heat. Contraindications: peptic ulcer of the stomach or duodenum, severe dysfunction of the liver and kidneys, individual sensitivity to the components of the drug, pregnancy 3rd trimester, lactation. Children under 3 years old.
- Sulidin. Indicated for periarthritis, osteoarthritis, tendinitis, lumbago, during sprains, inflammatory processes in the musculoskeletal system. Contraindications: hypersensitivity to the components of the drug, dermatitis and infectious skin diseases, pregnancy, lactation. Children's age up to 12 years.
Among other drugs that are classified as generics, there are the following:
- Auronym. Produced in India. Relieves the inflammatory process in the postoperative period, relieves fever, alleviates pain during acute inflammation in the upper respiratory tract, and is used by women with dysmenorrhea. It also treats diseases associated with arthritis.
- Actosulide. This medicine is produced in Serbia and Montenegro. Indications for use: headache and toothache, dysmenorrhea, various arthritis, tenditis, bursitis, myalgia and the like.
- Mesulide. Supplier Ireland. Primary dysmenorrhea, acute pain due to inflammatory processes in the body, symptomatic treatment of osteoarthritis with pain.
- Cockstral. Produced in the Czech Republic. Arthritis of various etiologies, pain after surgery and after injuries, algodismenorrhea, feverish conditions, dental pain and headaches.
What is the difference between analogues and the original
When a drug is first developed, a pharmaceutical company buys a patent for it. That is, the brand and product names. A patent is the right of the owner and no one except this company will be able to produce such products.
A patent is established for a certain period of time by law. In this way, pharmacological production recoups the costs of research and testing that were carried out with the drug.
An analogue is a repetition of a medical product that is no longer protected by a patent. Its components partially or completely copy the original; they have the same effective effect, but are not protected by a security document.
The pricing policy of generics is much lower, since their release does not require additional research or testing. After all, all chemical formulas are borrowed from the original drugs.
Analogues, unlike the original medicine Nise, have different colors, shapes and tastes.
But the most important difference is the side effects. They should be carefully studied in order to stop taking them in situations where they appear.
Among the advantages of analogues are the following:
- Lower price;
- Such drugs are well studied for effectiveness and safety before they are released;
- A variety of similar tablets give you the opportunity to choose what to take;
- People with different income levels can use a generic drug.
Among the disadvantages, the following are noted:
- Manufacturers of such drugs do not fully disclose the entire production secret. Therefore, during the production of analogues, they may not adhere to the full technology and not report all the components of the product;
- Some manufactured analogues of Nise have a low level of quality;
- The original Nise tablets are produced in laboratories using high-tech equipment and with a high degree of purification of the material. Small pharmaceutical production may not have such capabilities, so they use old equipment and inexpensive auxiliary elements.
- In our country, they do not practice assigning qualifications to generics, as they do abroad, so it is difficult for our customers to truly evaluate the effectiveness of one or another analogue.
How to choose a generic?
Of course, many people prefer to buy cheaper analogues of medicines, because the originals are simply unaffordable for some parts of the population.
But, before you buy an analogue of Nise, tell your doctor. Perhaps the medicine is not suitable for you or there are serious contraindications.
And some tips on how to choose the right generic:
- First: never replace the original medicine with an analogue on your own. This should be done by your doctor. He is the one who knows what will suit you as a replacement.
- You should only purchase generics from large pharmacy chains. Firstly, good specialists work there, and they will be able to advise you on this issue. Secondly, in such places there is less risk of buying a fake.
- After purchasing the drug, carefully read the instructions. The abstract must be on high-quality paper, with a clear font. It must include the address and telephone number of the pharmaceutical company that manufactured the analogue.
- The cheapest products can cost this much because they are made from low-quality material or use old equipment. Therefore, you should not give them preference.
Let's sum it up: there are many analogues, but you shouldn't replace the original with a generic one yourself; it's better to consult a doctor for help. He will explain to you the advisability of such a replacement; sometimes it happens that a disease requires the original, because it acts much faster than the analogue.
All other cases: generics have long won the hearts of people for their ability to help and low cost.
Nise – the main active ingredient is nimesulide. The drug belongs to the group of highly selective non-steroidal anti-inflammatory drugs.
Nise tablets are prescribed for pain syndromes of varying strength and origin. These include joint pain, dental pain, and menstrual pain. The drug has anti-inflammatory and antipyretic properties. Available both in tablet form and in the form of suspensions.
Medicinal educational program
Sometimes our legislative bodies like to send drugs without re-registration, ban them from being imported into the country, and so on drag out bureaucratic bagpipes. What to do when your favorite pills disappear from pharmacy shelves?
- Do not panic.
- Ask your doctor if there is an analogue of your favorite medicine. If you can’t see a doctor, you can get all the information about the drug from the pharmacist at the pharmacy.
There is an analogue for any medicine. Substitutes are divided into:
- Generics– that is, the active substance is the same, but the names are different. The effect that such tablets have is no different from patented drugs. But the cost may be significantly lower.
- Complete analogue- that is, the effect of the medicine is similar, but the active ingredients are different. Costs can also vary significantly.
The drug "Nise". Generics
The main active ingredient of the drug "Nise" is nimesulide. What drugs with the same composition can the pharmacist suggest?
- Aponil– active ingredient nimesulide. Available in the form of tablets with a dosage of 100 mg. Manufacturer: Cyprus company Melokemi LTD.
- Mesulid- Produced in Romania by Rompharm. This is a soluble form for preparing a suspension. One sachet contains 2 g of the drug, the dosage is also 100 mg.
- Nimesil– manufacturer Italy. Soluble form, dosage 100 mg in 1 sachet.
- Nimesulide– producers Romania and Macedonia. Soluble form.
- Nimika- Manufacturer: India. Presented in the form of tablets with a dosage of 50 mg and 100 mg.
- Nimulid- Manufacturer: India. Available in the form of lozenges, gel, or just tablets in various dosages.
All these drugs work the same way. Soluble forms “nimesil” and “nimesulide” begin to act faster. This is not a pharmacological feature of these drugs; soluble forms are simply absorbed faster into the mucous membranes of the mouth and stomach than tablet forms.
If the pain is severe or the body temperature rises sharply, then it is more advisable to use soluble forms of the drug.
The choice of drugs is sufficient, and if you don’t find Nise at the pharmacy, then you can safely buy any analogue from the list above.
Other drugs in the same class
There are medications in the same class as Nise - non-steroidal anti-inflammatory drugs. Prescribed for the same diseases as Nise.
- Denebol– presented on the market in 3 dosage forms – gel for external use, ampoules and tablets. The main active ingredient is roferocoxib. Indications for use: pain of various etiologies, rheumatoid and other arthritis, neurological diseases. Both injections and tablets are taken once a day. Manufacturer – India, Mepro Pharmaceuticals Pvt. Ltd.
- Movalis– active ingredient – meloxicam. In pharmacies it is presented in the form of tablets, rectal suppositories, injections. Dosage 7.5 and 15 mg. 1 ampoule or tablet per day is also prescribed. Produced in Germany by the Boehringer Ingelheim concern.
- Meloxicam– also available in tablets and injection solutions. Also prescribed is 1 tablet or injection per day. Do not use to treat children under 15 years of age.
- Arcoxia– indications – pain syndrome, treatment of arthritis of various etiologies and genesis. Available in 3 different dosages - 120 mg, 90 mg, 60 mg. Take 1 tablet per day.
These drugs are prescribed mainly for various problems with joints, muscles, ligaments, for the treatment of the spine, and neuralgia. The above medications have a strong analgesic and anti-inflammatory effect and can quickly reduce body temperature.
In this regard, they are superior to Nise. But if it is only necessary to reduce the temperature during an infectious disease, then it is better not to use these medications.
All drugs in this group have a lot of side effects and contraindications. Joint inflammation is a good reason to use Meloxicam, Denebol or Arcoxia. In this case, the potential benefit of the drug is much higher than the potential harm.
In the case of body temperature elevated to 38 degrees and a runny nose, their use is unjustified.
"Nise" and its analogues at elevated body temperature
Paracetamol or Ibuprofen will help relieve mild pain and reduce temperature during a cold. Both drugs belong to the same pharmacological class of substances – non-steroidal anti-inflammatory drugs.
They have weak analgesic properties, but are excellent at reducing body temperature. No worse than Nise or other nimesulide preparations. These drugs have few side effects and do not irritate the mucous membranes of the stomach and intestines.
Paracetamol and ibuprofen can be given to children almost from birth. These are over-the-counter drugs and should be in any mother's medicine cabinet.
Nise. conclusions
- If the pharmacy does not have the medicine you need, consult your pharmacist about replacing it with an analogue with the same active ingredient and in the same dosage.
- If you cannot find a complete analogue, then consult your doctor about replacing it with a drug that belongs to the same pharmacological group. Not with the pharmacist, but with the attending physician!
- Do not use strong drugs without a doctor's prescription. The body tends to get used to medications. And in the future the drug may simply not work.
"Nise" belongs to the group of non-steroidal anti-inflammatory drugs. The product is used for pain syndromes and inflammatory processes. Let's look at basic information about the drug and what analogues of Nise exist.
Composition, release form
The composition of the drug "Nise" includes nimesulide. It is this that is the active ingredient. It also contains additional components, such as talc, corn starch, calcium hydrogen phosphate, magnesium stearate. The list may vary depending on the release form.
There are several forms of release of "Nise":
- pills;
- suspension;
- gel.
The choice of one or another type of remedy depends on the type of disease.
Indications for use
Indications for use of "Nise" are the presence of:
- toothache;
- migraine;
- menstrual pain;
- pain caused by surgery or injury;
- inflammation of ligaments, tendons.
The drug is also prescribed during the treatment of diseases such as:
- bursitis;
- arthralgia;
- osteoarthritis;
- arthritis of various etiologies;
- algodismenorrhea;
- tendinitis;
- gout;
- rheumatism;
- lumbago;
- radiculitis;
- sciatica.
Before using the drug, you should consult your doctor!
Contraindications for use
It is important to know not only the indications for use of Nise, but also the cases when the use of the drug is prohibited. You will have to look for a replacement drug if the patient has:
- ulcers of the stomach or duodenum during an exacerbation;
- stomach or intestinal bleeding;
- kidney or liver dysfunction;
- arterial hypertension;
- heart failure;
- diabetes mellitus;
- hypersensitivity to the components of the drug;
- alcoholism or drug addiction.
Nise pain relief tablets and gel are not prescribed to children under 12 years of age. If the baby is less than 2 years old, the suspension is not suitable, as is the case for pregnant women in the third trimester and breastfeeding mothers. The drug in gel form should not be applied to damaged skin, as well as in case of infectious lesions and dermatoses.
Side effects
So, we found out what Nise helps with. It must be remembered that, like any other medication, this drug can cause various side effects. In the instructions for use, the manufacturer warns about possible reactions:
- Skin: rash, redness, itching, hyperhidrosis, angioedema, urticaria, facial swelling, toxic epidermal necrolysis, Stevens-Johnson syndrome.
- From the nervous system: headaches, dizziness, increased drowsiness, Reye's syndrome.
- From the kidneys: edema, renal dysfunction, urinary retention, dysuria, oliguria, hematuria, interstitial nephritis.
- From the digestive system: nausea, vomiting, diarrhea or constipation, flatulence, stomatitis, melena, gastritis or ulcer, acute hepatitis, cholestasis, gastrointestinal exacerbation.
- From the respiratory system: bronchospasm, dyspnea, asthma.
- From the cardiovascular system: fluctuations in blood pressure, tachycardia, arterial hypertension, hot flashes.
- Blood disorders: thrombocytopenia, anemia, purpura, pancytopenia, eosinophilia.
- From the immune system: anaphylaxis, allergic reactions.
Other side effects are also possible, such as blurred vision, asthenia, hypothermia, hyperkalemia and mental disorders (nightmares, anxiety, nervousness).
Directions for use and doses
“Nise” in gel form is applied to the skin no more than 4 times a day. As a rule, such therapy lasts 10 days.
Suspension and tablets "Nise" are intended for internal use. The dosage and duration of treatment are determined individually, it all depends on the patient’s age, the nature of the disease and some other factors. In most cases, the patient has to take the drug twice a day.
Many people are interested in the question of how long Nise lasts. First of all, it all depends on the cause of the pain and its degree. The average value is within 4-6 hours.
Analogs
There are many analogues of “Nise”, which have the same active substance and have a similar mechanism of action. As an example, we can recall such drugs as:
- "Aponil";
- "Kokstral";
- "Nimesil";
- "Nimulid";
- "Nimegesic";
- "Remisid";
- "Remesulide";
- "Sigan";
- "Nimid";
- "Mesulide";
- "Sulaidin";
- "Ameolin";
- "Nimesulide".
To have an idea of Nise’s analogues, let’s look at brief instructions for use for some of them.
"Nimesil"
The first analogue of “Nise” that we will consider is “Nimesil”. The drug contains nimesulide as an active ingredient. The product is produced in the form of a powder for preparing a suspension.
"Nimesil" is used for:
- pain syndrome of various etiologies;
- bursitis;
- tendinitis;
- arthritis;
- dysmenorrhea;
- gynecological diseases;
- otorhinolaryngological diseases;
- injuries.
The product is also used in the postoperative period.
As a rule, the patient is prescribed the minimum effective dose that will help reduce pain. The daily dose varies depending on the age of the patient, it varies between 100-200 mg. The course of treatment is 15 days.
Contraindications to the use of Nimesil are largely the same as for Nise and other non-steroidal anti-inflammatory drugs.
"Nimulid"
Sometimes patients are faced with a choice: buy “Nise” or “Nimulid”. Which drug is better?
Just like Nise, Nimulid is produced in the form of syrup, tablets and gel. The main active ingredient of the drug is nimesulide.
"Nimulid" has antipyretic and anti-inflammatory effects, can relieve pain and reduce platelet aggregation. What “Nise” helps with was discussed above. Indications for the use of Nimulid are largely the same. The product is used in the treatment of various diseases of the ENT organs, musculoskeletal system, dentistry and gynecology.
Contraindications for use and side effects are also similar to those of the drug in question.
As you can see, there are no significant differences between “Nise” and “Nimulid”.
"Sigan"
This analogue of “Nise” is produced in the form of tablets. The drug has two active ingredients - nimesulide and dicyclomine hydrochloride.
Unlike "Nise", "Sigan" can be given to children starting from the age of 6. The drug is usually prescribed for:
- severe headache;
- dysmenorrhea;
- osteoarthritis;
- bursitis;
- arthrosis;
- tendovaginitis;
- diseases of the ENT organs;
- renal, hepatic or intestinal colic;
- biliary dyskinesia;
- spasm of the bladder or ureters;
- pain in the postoperative period;
- pain syndrome of various etiologies.
The duration of treatment with the drug should not exceed 15 days.
"Nimesulide"
This drug could not have been given special attention, since its indications, contraindications for use and side effects completely coincide with Nise. The only thing that distinguishes it from the drug we are considering is its much lower cost. Therefore, patients who are looking for cheaper analogues of Nise should pay attention to Nimesulide.
Analogues with other active ingredients
There are products that contain not nimesulide, but another active substance. But the basic principle of their operation remains the same. There are many such drugs, so let’s remember a few of the most famous ones.
With diclofenac sodium as active substance:
- "Diclofenac";
- "Algozan gel";
- "Voltaren";
- "Arguette";
- "Diklak gel";
- "Diclobene";
- "Doloxen gel";
- "Olfen";
- "Naklofen";
- "Clodifene";
- "Feloran gel";
- "Rapten gel".
With keptophrene as an active ingredient:
- "Keptophrene";
- "Ketonal";
- "Artrocol";
- "Valusal";
- "Nobi gel";
- "Ketum-gel";
- "Ultrafastin";
- "Fastum gel";
- "Fort-gel";
- "F-gel."
With menthol and/or methyl salicylate:
- "Dolaren gel";
- "Dicloran plus";
- "Fanigan Fast";
- "Bol-Ran gel";
- "Cinepar Active gel.
Also, analogues of “Nise” can be based on phenylbutazone, for example, “Butadione” ointment.
Let's look at brief instructions for use for several more drugs.
"Diclofenac"
Pharmacists often hear from patients the question of which is better, Nise or Diclofenac. The time has come to give a reasoned answer to it.
To begin with, we note that these two drugs have different active ingredients. Diclofenac sodium tablets, ointments, gels and suppositories are based on diclofenac sodium. The drug is used for:
- arthrosis;
- chronic polyarthritis;
- neuralgia and neuritis;
- spondyloarthrosis;
- acute attacks of gout;
- rheumatism of soft tissues;
- degenerative and inflammatory diseases of the joints;
- traumatic bruises;
- inflammatory swelling of soft tissues;
- myalgia and arthralgia;
- sprains of muscles, tendons and ligaments.
As you can see, the list of indications for the use of these two drugs has some differences. This means that it is quite difficult to determine exactly what is better “Nise” or “Diclofenac”. Both remedies show high effectiveness, although it was noted that the anti-inflammatory effect of the second remedy is much stronger. At the same time, “Nise” does not have such an aggressive effect on the human gastrointestinal tract and the body as a whole. It also has much fewer side effects compared to Diclofenac.
Therefore, before choosing one or another drug, it is important to decide on the result that you would like to get from the treatment. For severe pain, it is better to choose Diclofenac, and for moderate and weak pain, it is better to choose Nise.
Another important difference for many patients is the cost of drugs. In this regard, Diclofenac definitely “wins”, since its price is about 5 times lower.
"Fastum gel"
The active substance of the drug is ketoprofen. Additionally, the gel contains various auxiliary components, such as ethyl alcohol, water, neroli oil, carbomer, triethanolamine.
"Fastum Gel" has an anti-inflammatory effect and is able to penetrate deep into the tissue. At the same time, it is not addictive and does not have a systemic effect.
The drug is prescribed for pain caused by bruises, dislocations, sprains and other injuries, as well as lumbodynia and lumbago.
"Fastum gel" can be applied to the affected area up to two times a day, and treatment should not last more than 10 days.
As for side effects, there are not so many of them, and they are quite rare. To a greater extent, these are skin allergic reactions, which manifest themselves in the form of redness, itching, hives, rash, burning, eczema.
If absolutely necessary, the product can be used for treatment even during pregnancy and breastfeeding. A contraindication to its use is the presence of individual intolerance to ketoprofen or other components of the drug.
Today, a drug from the group of non-steroidal anti-inflammatory drugs Nise is one of the most popular and prescribed. However, despite its fairly high effectiveness, some patients may wonder what medicine can replace it. The selection of analogues is necessary in cases where the prescribed medicine does not have the desired therapeutic effect or cannot be taken for some other reason.
The main condition for changing the medication or adjusting the treatment regimen is a mandatory consultation with the attending physician, who conducted all the examinations and established the diagnosis. Changing your therapy on your own can be dangerous to your life and health, so never self-medicate. Next, we will talk in detail about the most popular analogues and outline some nuances regarding in which cases or for which pathologies one should give preference to one or another pharmaceutical product.
Analogs
There are a fairly large number of pharmaceutical drugs that can become substitutes. These may be drugs:
- with the same active ingredient as the original product;
- representatives of the same group of anti-inflammatory drugs, having a different main component, but realizing therapeutic effects through the same mechanism of action.
Whatever the reason for changing the medicine, the selection of an analogue should be carried out only with a doctor who knows all the nuances of the medicines and, if necessary, can prescribe tests or instrumental examinations that can help determine further tactics.
It is not possible to say unequivocally which medication is better, since each medication has its own pros and cons. It is necessary to decide what is best suited only on the basis of each specific therapeutic situation.
Ibuprofen or Nise: which is better?
The drugs belong to the group of non-steroidal anti-inflammatory drugs that act by inhibiting cyclooxygenase. The indications and contraindications of these medications are similar, since the drugs realize their therapeutic effects through the same mechanism, but there are also differences that influence the final choice.
When used orally, Nise begins to act faster, which is a very big advantage, especially when it comes to relieving acute pain. Ibuprofen can have a greater effect on the mucous membranes of the stomach and more often leads to the appearance of medicinal ulcers.
Despite the fact that the active components of these drugs are different, they cannot be taken at the same time, because this increases the risk of developing unwanted side complications.
Note! What is better for osteochondrosis? Most often in medical practice, Nise is prescribed for this disease. It has shown greater effectiveness, the duration of its administration is longer, and its effect on the body is gentle.
Ketanov and Nise: comparative characteristics
Medicines belong to different pharmaceutical groups and have different active chemical compounds. The drug Ketanov has a therapeutic effect due to the content of ketorolac, and Nise - thanks to nimesulide.
The main difference between Ketanov is that its analgesic effect is much superior to that of antipyretic, anti-inflammatory and decongestant. And Nise acts comprehensively, but at the same time eliminates pain to a lesser extent. Therefore, Ketanov is necessary when pain comes to the fore in the clinic, and Nise, when we see all the signs of inflammation (pain, hyperemia, swelling, hyperthermia) and want to influence each of them.
What to choose: Nimesil or Nise
The drugs being compared are very similar to each other, since they contain the same active ingredient. That is why the list of indications for their use is largely similar. The main difference, which can become a decisive factor when choosing a medicine, is the form of release of the drug. is available only in the form of granules intended for the preparation of a solution for internal use. Nise has a greater variety of produced forms.
Nimesil, due to the fact that it is taken in dissolved form, begins to act faster, since the active substance is immediately absorbed in the gastrointestinal tract and no time is wasted on dissolving the tablet or capsule.
When choosing, you must also be guided by the wishes of the patient, who can decide for himself which drug will be more convenient for him to use.
Which is better: Diclofenac or Nise
Both and Nise belong to the group of NSAIDs, so they are similar in many ways. Their pharmaceutical components are different, and therefore their mechanisms of action proceed along slightly different paths. Diclofenac blocks the enzyme cyclooxygenase types 1 and 2, and Nise more selectively blocks only the second type of this enzyme.
The greater specificity of Nise reduces the risk of side effects, and also contributes to less pathological effects on the gastric mucosa (ulcers and erosions develop less frequently). Patients with concomitant gastrointestinal problems should give preference to Nise.
Ketorol as an analogue
Ketorol is a drug that is used primarily to achieve an anesthetic effect, that is, it affects the pain syndrome, while it practically does not affect the other components of the inflammatory process (antiexudative and antipyretic effects are weakly expressed).
Nise is able to effectively fight local edema of inflammatory origin, reduce body temperature and generally block the progression of inflammation. However, its analgesic effect is not as pronounced as that of Ketorol.
Based on the above, the drug should be selected based on what predominates in the patient’s disease picture (pain or local inflammation).
Meloxicam and Nise: comparative characteristics
They belong to the same group of pharmacological drugs and have the same mechanism of action, which is the inhibition of COX-2. Both of the drugs described are quite modern and actually have fewer complications compared to previous generations of similar drugs.
The final decision on prescribing Nise or Meloxicam should be made by the doctor after conducting an examination and after prescribing the necessary laboratory and instrumental studies.
Which is better: Nurofen or Nise
Nurofen contains the pharmacological compound ibuprofen, which is also a member of the NSAID group. Their action is similar in many ways, however, when using Nise, the risk of complications is lower. Ibuprofen has a more negative effect on the gastric mucosa, so it is not recommended for use by patients with stomach diseases or a history of peptic ulcers.
Aertal as a substitute
The main active ingredient of Aertal is aceclofenac, which, like all other non-steroidal anti-inflammatory drugs, is involved in inhibiting the formation of prostaglandins (one of the main mediators of the inflammatory process) through its effect on cyclooxygenase. Nise is considered a more gentle drug, the use of which is easier to tolerate by patients (especially if we are talking about a long course of treatment).
Which is better: Arcoxia and Nise
Arcoxia is considered one of the best representatives of the NSAID group. This drug is well tolerated by the vast majority of patients. Arcoxia, like Nise, is a more gentle medicine for the mucous membrane of the digestive tube compared to representatives of non-steroidal anti-inflammatory drugs that do not selectively inhibit COX 1 and 2.
In general, Arcoxia and Nise are very similar to each other, so the choice of drug should depend on the individual characteristics of the patient’s body.
Movalis and Nise: comparative characteristics
Movalis and Nise have pronounced anti-inflammatory, antipyretic and analgesic effects. Both drugs affect all links and components of the inflammatory process. Nise is more often used for traumatic injuries of the musculoskeletal system, and Movalis is used in rheumatological practice to treat severe stages of various specific diseases.
What to choose: Celebrex or Nise
Celebrex contains celecoxib, which belongs to a new class of anti-inflammatory drugs. Celebrex is considered a more selective NSAID, which can reduce the risk of various complications and side effects. The cost of this drug is quite high and there is no reliable evidence that its advantages justify the stated price.
There have been no studies that could definitively say which of the drugs being compared is better.
Pentalgin as an analogue
Pentalgin is a combination drug that contains several active ingredients. They will provide a therapeutic effect. The main indication for prescribing this drug is pain, and this drug can relieve even very severe pain. Nise also has an analgesic effect, but it is not expressed to the same extent as Pentalgin.
It is not entirely correct to compare these drugs, since they have different points of application in the body, and the list of their indications varies significantly. The choice of drug depends only on the disease that requires treatment.
Table comparing drug analogues by cost. The last data update was 10/21/2019 00:00.
| Name | Price | |
|---|---|---|
| Diclofenac | from 14.00 rub. up to 309.00 rub. | |
| Nimesil | from 25.00 rub. up to 860.00 rub. | |
| Meloxicam | from 25.00 rub. up to 299.00 rub. | |
| Ibuprofen | from 30.00 rub. up to 97.00 rub. | |
| Ketorol | from 41.00 rub. up to 399.00 rub. | |
| Ketanov | from 55.00 rub. up to 111.00 rub. | |
| Pentalgin | from 62.00 rub. up to 330.00 rub. | |
| Nurofen | from 87.40 rub. up to 443.50 rub. | |
| Celebrex | from 185.00 rub. up to 1390.00 rub. | |
| Arcoxia | from 512.00 rub. up to 1610.00 rub. |
Article rating
Pain and inflammation cause a lot of unpleasant sensations, and when intense, they cause agony. In order to eliminate symptoms and treat inflammatory processes, drugs of the synthetic group are used, which include Nise, as well as its analogues.
About the drug
A drug that has an analgesic and anti-inflammatory effect in many pathological processes.
The effect of using a medicine is based on the body's reaction to its composition. The active substance is nimesulide.
Available in the form of regular and dispersible tablets, also in the form of medicinal powder for the preparation of suspension and gel for external use.
Regardless of the form of release, indications for use are pain and inflammation in diseases:
- arthritis of psoriatic or rheumatoid type;
- sciatica or radiculitis;
- joint disorders due to rheumatism or gout;
- spondyloarthritis or osteochondrosis;
- lumbago or arthritis;
- myalgia or arthralgia;
- feverish condition;
- inflammation of soft tissues after injuries;
- bursitis or tendon damage;
Nise tablets and suspension are used to relieve pain, dental pain, menstrual pain and headaches. Nise gel is recommended for traumatic injuries and after operations performed on muscles, bones or joints.
The instructions for use of the drug warn about the undesirable use of the drug in tablets and suspensions for pathologies:
- erosions or ulcers on the mucous membranes of the gastrointestinal tract;
- liver/kidney dysfunction;
- aspirin triad.
Gel Nise is not prescribed if the skin is affected by infection or dermatoses.
Absolute contraindications for any form of release of the analogue are considered to be the period of pregnancy/lactation and sensitivity to the existing composition.
The drug has many side effects, but they most often occur with an overdose or the presence of contraindications. In case of an adverse reaction, the patient experiences symptoms:
- disorders of the stomach and intestines;
- migraine;
- allergies (including anaphylactic shock);
- circulatory disorders.
The average price for Nise gel and tablets is 200 rubles, suspension powder is 300 rubles.
Similar medicines
If necessary (due to the high price, contraindications, side effects, etc.), you can replace Nise with analogues. Depending on the indications, as well as the reason for searching for a substitute, the doctor may prescribe analogs that are cheaper or more expensive than the original. It should be borne in mind that some analogues of this group are sold in pharmacy chains only with a prescription.
Analogues of Nise:
- Nimesulide;
- Ibuprofen;
- Nimulid;
- Nimesil;
- Aertal;
- Aceclofenac.
Nimesulide and Ibuprofen are substitutes that cost much less than the original.
Nimesulide
Direct analogue of Nise gel and tablets. The medicine is used for therapy for inflammatory diseases of the musculoskeletal system and other body systems. Also, tablets and gel for external application are used as a strong pain reliever for various forms of pain.
The active substance has a name identical to the name of the drug - Nimesulide. Tablets contain 100 mg. the main component and additional substances necessary to enhance the effect of the composition.
List of direct indications:
- osteoarthritis;
- dysmenorrhea;
- migraine;
- toothache;
- injuries to muscles, joints or bones;
- pathologies of the musculoskeletal system.
An analogue of Nise tablets is contraindicated in case of damage to the gastrointestinal mucosa, heart failure, and a substitute in the form of a gel is contraindicated in case of open wounds and infectious processes on the skin.
General contraindications:
- children's age (up to 12 years);
- intolerance to the components of the composition;
- blood pathologies;
- kidney/liver diseases;
- alcohol addiction;
- allergy to one or more substances from the composition of the drug.
A cheap analogue of Nise can cause side symptoms:
- pain in the epigastric region, feeling of nausea, severe heartburn, change in stool;
- constant dizziness or drowsiness;
- erythema, rash or urticaria;
- slower removal of fluid from the body, swelling;
- thrombocytopenic purpura.
The price of the drug Nimesulide is from 80 rubles.
Ibuprofen
Another cheap analogue of Nise gel and other forms of release is Ibuprofen. The drug has a wide range of effects and is recommended for providing analgesic, antipyretic, and anti-inflammatory effects.
Release form:
- tablets (extended, regular and for resorption);
- extended-release capsules;
- suspension;
- caviar gel
The active component of the analogue is ibuprofen.
Instructions for use include the following indications:
- signs of a viral disease (ARVI/flu);
- arthritis (psoriatic), osteoarthritis and spondylosis;
- migraine, myalgia and neuralgia;
- spinal artery syndrome, Barré-Lieu or nephrotic;
- bursitis, tendinitis and hematomas;
- hypotension, ankylosing spondylitis, fever;
- injury to soft tissue or bones.
An inexpensive analogue is also used for therapy for sprains of ligament tissue, arthritis (rheumatoid), articular syndrome or radiculitis.
The list of contraindications to the use of medications is extensive. The main contraindications for Ibuprofen include:
- the presence of ulcers or erosions on the walls of the stomach or intestines (except for the use of gel);
- sensitivity to the existing composition;
- pathologies of the optic nerve and deviations regarding the function of color visual perception;
- Asperin asthma;
- hypertension, amblyopia or scotoma;
- impairment of the full functioning of the kidneys/liver;
- heart failure;
- hemophilia, edema, leukopenia;
- third trimester pregnancy.
The Russian drug causes side effects that affect the nervous, digestive, circulatory and urinary systems. An allergic reaction is also possible.
The cost of medicines is from 70 rubles, depending on the form prescribed by the specialist.
Nimesil
An anti-inflammatory drug with an analgesic effect, Nimesil, is included in the list of drugs that are analogues of Nise.
The drug is produced only in the form of a powder for dissolution and preparation of a suspension. The active component is nimesulide.
Indications:
- infectious inflammation;
- inflammatory and degenerative processes affecting the musculoskeletal system;
- gynecological, urological and vascular inflammatory pathologies;
- post-traumatic complications;
- dental diseases;
- migraine.
Nimesil has earned positive reviews for eliminating pain during menstruation and as an antipyretic.
- inflammatory processes in the gastrointestinal tract;
- installation of a shunt in the aorta;
- fever;
- intolerance to any constituent substances.
The body’s negative reaction to the Nise analogue is expressed in the following symptoms: heart rhythm disturbances, headaches, intestinal dysfunction and allergies.
The price for Nimesil is from 500 rubles.
Nimulid
A good analgesic and pain reliever is Nimulid, developed on the basis of nimesulide as an active ingredient. Among the drugs that replace Nise, Nimulid is considered one of the most effective; in addition, the drug has several release forms. Lingual, regular tablets and suspension. Also, the drug in the form of an ointment can replace Nise gel.
- arthritis of rheumatoid or psoriatic nature;
- bursitis, musculoskeletal injuries;
- osteochondrosis or spondyloarthritis;
- articular gouty syndrome;
- myalgia.
Contraindications:
- erosive - ulcerative damage to the mucous membrane of the walls of the stomach or intestines;
- diseases developing in the liver or kidneys;
- tendency to allergies, including intolerance to the composition;
- pregnancy/lactation.
Side symptoms often include headaches and severe weakness. When treated with ointments, a local allergic reaction is possible.
The analogue is cheaper than Nise - from 170 rubles.
Aertal
The non-steroidal drug Airtal is a substitute for Nise in three main forms (tablets, gel and suspension). However, unlike Nise, Aertal contains the main component - aceclofenac, which eliminates pain and prevents the process of inflammation.
- periarthritis in the shoulder and shoulder blade area;
- lumbago;
- rheumatism progressing in soft tissues;
- osteoarthritis;
- dental pain;
- rheumatoid arthritis;
- ankylosing spondylitis.
The cream can be used to relieve swelling of tissues and eliminate pain of a limited nature (for example, due to injuries).
Contraindications:
- damage to the walls of the gastrointestinal tract;
- hives;
- bronchospasm;
- medicinal rhinitis;
- liver dysfunction;
- circulatory pathologies;
- hyperkalemia;
- a woman carrying a fetus;
- breastfeeding;
- childhood.
Before starting treatment with Airtal, you should pay attention to signs of side effects associated with dysfunction of the stomach/intestines and nervous system. An allergic reaction is possible.
The price for Aertal is from 270 rubles.
Aceclofenac
The drug Aceclofenac with analgesic, antipyretic and anti-inflammatory effects belongs to the group of analogues of the drug Nise.
There is only one release form - tablets, which contain a medicinal substance - aceclofenac.
Indications for symptomatic therapy:
- spondylitis;
- arthritis;
- periarthritis;
- osteoarthritis;
- inflammation of soft tissues (rheumatoid).
Contraindications:
- age of patients under 18 years;
- gastrointestinal pathologies associated with the presence of ulcers or erosions;
- aortic bypass;
- heart failure;
- lactation/pregnancy;
- allergy to the medicinal composition of the drug.
Side effects manifest themselves in the digestive tract, circulatory and nervous systems, as well as in the form of allergies.
The cost of the Nise analogue is from 230 rubles.
Conclusion
Taking into account all the features of treatment with drugs of this group, experts are of the opinion that Nise’s analogues have more disadvantages than the original. However, it is impossible to determine what is best for the patient in each specific case. Sometimes cheaper analogues are more effective than the original drug with a high cost. The effect of drugs on the body often does not depend on price, so the choice of drugs should be trusted only to the attending physician.